abstract：BACKGROUND:Although the dopamine precursor L-3, 4-dihydroxyphenylalanine ( l -dopa) remains the gold standard pharmacological therapy for patients with Parkinson's disease (PD), long-term treatment with this drug has been known to result in several adverse effects, including l -dopa-induced dyskinesia (LID). Recently, ...

journal_title：BMC complementary and alternative medicine

authors： Ahn S,Song TJ,Park SU,Jeon S,Kim J,Oh JY,Jang J,Hong S,Song MA,Shin HS,Jung YR,Park HJ

更新日期：2017-04-19 00:00:00

abstract：BACKGROUND:Mitochondrial dysfunction and oxidative stress are the main toxic events leading to dopaminergic neuronal death in Parkinson's disease (PD) and identified as vital objective for therapeutic intercession. This study investigated the neuro-protective effects of the demethoxycurcumin (DMC), a derivative of curc...

journal_title：BMC complementary and alternative medicine

authors： Ramkumar M,Rajasankar S,Gobi VV,Dhanalakshmi C,Manivasagam T,Justin Thenmozhi A,Essa MM,Kalandar A,Chidambaram R

更新日期：2017-04-18 00:00:00

abstract：BACKGROUND:JC-001 is a Chinese medicine that can modulate the immunity in Hepa 1-6 tumor-bearing mice, and we questioned whether JC-001 can serve as efficient adjuvant chemotherapy. We aimed to identify a novel approach for enhancing cis-diamminedichloroplatinum (II) (CDDP)-based chemotherapy by immunomodulation. METH...

journal_title：BMC complementary and alternative medicine

authors： Chuang MH,Jan MS,Chang JT,Lu FJ

更新日期：2017-04-11 00:00:00

abstract：BACKGROUND:Burkittlymphoma(BL) is the most common childhood cancer in Cameroon with a reported incidence of 3 per 100,000 children under 15 years in the Northwest region. Treatment at three Baptist mission hospitals has a recorded cure rate of over 50%. Traditional medicine(TM) is recognized by the national health syst...

journal_title：BMC complementary and alternative medicine

authors： Afungchwi GM,Hesseling PB,Ladas EJ

更新日期：2017-04-11 00:00:00

abstract：BACKGROUND:Glutamate (an endogenous excitatory neurotransmitter) at high concentrations contributes to the development of neurodegenerative diseases. Aronia melanocarpa (A. melanocarpa) berries contain anthocyanins and have high antioxidant activities. In this study, we evaluated whether A. melanocarpa berries could pr...

journal_title：BMC complementary and alternative medicine

authors： Lee HY,Weon JB,Ryu G,Yang WS,Kim NY,Kim MK,Ma CJ

更新日期：2017-04-11 00:00:00

abstract：BACKGROUND:Free radicals have been implicated in the pathogenesis of diverse metabolic disorders including cancer. Therefore, fighting against free radicals has become an important strategy in the prevention or treatment of such diseases, in addition to direct or indirect anticancer chemotherapy. Sarcocephalus pobeguin...

journal_title：BMC complementary and alternative medicine

authors： Mfotie Njoya E,Munvera AM,Mkounga P,Nkengfack AE,McGaw LJ

更新日期：2017-04-04 00:00:00

abstract：BACKGROUND:Aim of the present study was to evaluate anti-inflammatory activity of newly developed polyherbal formulations DF1911, DF2112 and DF2813. These newly developed formulations are modifications of Dashamoola, a well known Ayurvedic formulation, along with addition of new plants. METHODS:Complete Freund's adjuv...

journal_title：BMC complementary and alternative medicine

authors： Nagarkar B,Jagtap S

更新日期：2017-04-04 00:00:00

abstract：BACKGROUND:The use of CAM by pregnant women is very popular in developed countries. The trend is increasing globally and lack of evidence of safety particularly when used during pregnancy may lead to complications. Pregnancy is a vulnerable period especially during the first trimester. There is scarcity of empirical ev...

journal_title：BMC complementary and alternative medicine

authors： Onyiapat JL,Okafor C,Okoronkwo I,Anarado A,Chukwukelu E,Nwaneri A,Okpala P

更新日期：2017-04-04 00:00:00

abstract：BACKGROUND:Antioxidant and anti-inflammatory properties of honey have been largely recognized by various studies. Almost all of the potential benefits are associated with polyphenol content. Honey varieties from the arid region are reported to be rich in polyphenols, but data related to its bioactivity in vitro is grea...

journal_title：BMC complementary and alternative medicine

authors： Hilary S,Habib H,Souka U,Ibrahim W,Platat C

更新日期：2017-03-29 00:00:00

abstract：BACKGROUND:Complementary traditional Chinese medicine (TCM) has been used to treat patients with cerebral palsy (CP). However, large-scale surveys examining its use in the treatment of CP and associated disorders are lacking. METHODS:We enrolled 11,218 patients ≤ 18 years of age with CP in the Taiwanese National Healt...

journal_title：BMC complementary and alternative medicine

authors： Liao HH,Yen HR,Muo CH,Lee YC,Wu MY,Chou LW,Sun MF,Chang TT

更新日期：2017-03-14 00:00:00

abstract：BACKGROUND:The role of plants for discovery of therapeutic potential accentuates the need to know their biological attributes. The present study aims to comprehend the biological attributes of Rhus punjabensis, an unexplored traditional medicinal plant. METHODS:Leaf and stem extracts of R. punjabensis prepared in 11 d...

journal_title：BMC complementary and alternative medicine

authors： Tabassum S,Ahmed M,Mirza B,Naeem M,Zia M,Shanwari ZK,Khan GM

更新日期：2017-03-09 00:00:00

abstract：BACKGROUND:The brain is secondarily harmed by pathological, physiological, and biological reactions that are caused by traumatic brain injury (TBI). Rhein, a significant composition of Rhubarb, is a well-known traditional Chinese treatment method and has a strong oxidation-resisting characteristic, but Rhein's mechanis...

journal_title：BMC complementary and alternative medicine

authors： Xu X,Lv H,Xia Z,Fan R,Zhang C,Wang Y,Wang D

更新日期：2017-03-07 00:00:00

abstract：BACKGROUND:Lung cancer is one of the leading causes of cancer related deaths worldwide. Marine microalgae are a source of biologically active compounds and are widely consumed as a nutritional supplement in East Asian countries. It has been reported that Chlorella or Chlorella extracts have various beneficial pharmacol...

journal_title：BMC complementary and alternative medicine

authors： Lin PY,Tsai CT,Chuang WL,Chao YH,Pan IH,Chen YK,Lin CC,Wang BY

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:Much research has been done in Northeast Asia to show the efficacy of traditional medicine. While MEDLINE contains many biomedical articles including those on traditional medicine, it does not categorize those articles by specific research area. The aim of this study was to provide a method that searches for...

journal_title：BMC complementary and alternative medicine

authors： Kim SK,Nam S,Kim S

更新日期：2017-01-28 00:00:00

abstract：BACKGROUND:In ayurvedic traditional medicine Gentiana kurroo Royle (family; Gentianaceae) is used to treat several metabolic diseases. This plant is rich in various compounds belonging to flavonoids and glycosides. Till now little work has been carried out on immunomodulatory and anti-inflammatory potential of this pla...

journal_title：BMC complementary and alternative medicine

authors： Mubashir K,Ganai BA,Ghazanfar K,Akbar S,Rah B,Tantry M,Masood A

更新日期：2017-01-28 00:00:00

abstract：BACKGROUND:Currently, feasible medical treatments are hitherto not satisfying to relieve pSS symptoms, which concerns numbers of clinical doctors. Acupuncture seems to be an alternative to treat pSS and conduces to good symptomatic results. However further research is necessary. This trial is to investigate the efficac...

journal_title：BMC complementary and alternative medicine

authors： Jiang Q,Zhang H,Pang R,Chen J,Liu Z,Zhou X

更新日期：2017-01-19 00:00:00

abstract：BACKGROUND:Complementary and alternative medicine (CAM) use is popular in former Soviet Central Asian countries including Mongolia. However, no studies are available on CAM use among patients with cancer in countries of this region. The aim of this research is to describe the prevalence and patterns of CAM use by patie...

journal_title：BMC complementary and alternative medicine

authors： Oyunchimeg B,Hwang JH,Ahmed M,Choi S,Han D

更新日期：2017-01-19 00:00:00

abstract：BACKGROUND:Nymphaea alba L. represents an interesting field of study. Flowers have antioxidant and hepatoprotective effects, rhizomes constituents showed cytotoxic activity against liver cell carcinoma, while several Nymphaea species have been reported for their hepatoprotective effects. Leaves of N. alba have not been...

journal_title：BMC complementary and alternative medicine

authors： Bakr RO,El-Naa MM,Zaghloul SS,Omar MM

更新日期：2017-01-17 00:00:00

abstract：BACKGROUND:Punica granatum (pomegranate), an edible fruit originating in the Middle East, has been used as a traditional medicine for treatment of pain and inflammatory conditions such as peptic ulcer. The numerous risks associated with nonsteroidal anti-inflammatory drugs (NSAIDs) for treatment of pain and inflammatio...

journal_title：BMC complementary and alternative medicine

authors： BenSaad LA,Kim KH,Quah CC,Kim WR,Shahimi M

更新日期：2017-01-14 00:00:00

abstract：BACKGROUND:Osteosarcoma is the most common bone tumor and is associated with a poor prognosis. Conventional therapies, surgery and chemotherapy, are still the standard but soon reach their limits. New therapeutic approaches are therefore needed. Conventional aqueous mistletoe extracts from the European mistletoe (Viscu...

journal_title：BMC complementary and alternative medicine

authors： Kleinsimon S,Kauczor G,Jaeger S,Eggert A,Seifert G,Delebinski C

更新日期：2017-01-07 00:00:00

abstract：BACKGROUND:Rhodiola crenulata is traditionally used as a folk medicine in Tibet for preventing high-altitude illnesses, including sudden cardiac death (SCD). The cardio-protective effects of Rhodiola crenulata root extract (RCE) against hypoxia in vivo have been recently confirmed. However, the way in which RCE produce...

journal_title：BMC complementary and alternative medicine

authors： Hsu SW,Chang TC,Wu YK,Lin KT,Shi LS,Lee SY

更新日期：2017-01-07 00:00:00

abstract：BACKGROUND:Ischemic stroke is the third leading cause of death in adults worldwide and is the first leading cause of long-term disability. Neurogenesis plays an important role in promoting behavioral recovery after stroke. Huatuo Zaizao pill (HT), a traditional Chinese medicine, has been used clinically in China to pro...

journal_title：BMC complementary and alternative medicine

authors： Duan S,Wang T,Zhang J,Li M,Lu C,Wang L,Zou Y,Fu F

更新日期：2017-01-05 00:00:00

abstract：BACKGROUND:In Shaanxi province, China, the aqueous extract of Rubia cordifolia's aerial part (AERCAP) is traditionally used to manage diarrhea. However, there is no scientific evidence to verify the safety and efficacy of its use. The aim of this study was to investigate the anti-diarrheal and anti-inflammatory effects...

journal_title：BMC complementary and alternative medicine

authors： Gong XP,Sun YY,Chen W,Guo X,Guan JK,Li DY,Du G

更新日期：2017-01-05 00:00:00

abstract：BACKGROUND:Bitter Melon (BM) has been used as a functional food in traditional Chinese and Indian medicine for many generations and has gained a great deal of attention due to its apparent benefits in moderating some of the pathogenic processes in a variety of inflammatory conditions. BM extract (BME) has been shown to...

journal_title：BMC complementary and alternative medicine

authors： Kunde DA,Chong WC,Nerurkar PV,Ahuja KD,Just J,Smith JA,Guven N,Eri RD

更新日期：2017-01-03 00:00:00

abstract：BACKGROUND:Musk is widely used in clinical practice for its anti-cancer properties. Here, we treated various types of cancer using musk to determine which cancers are sensitive to musk treatment. We also compared effects of native musk and synthetic musk ketone in cancer cells. Furthermore, we investigated mechanisms u...

journal_title：BMC complementary and alternative medicine

authors： Xu L,Cao Y

更新日期：2016-12-08 00:00:00

abstract：BACKGROUND:Inflammatory bowel disease (IBD) is characterized by chronic or relapsing immune system activation and inflammation within the gastrointestinal tract. The lack of safety and efficacy of standard therapies, the use of food supplements for managing IBD is increasing, and many studies have reported that various...

journal_title：BMC complementary and alternative medicine

authors： Woo JK,Choi S,Kang JH,Kim DE,Hurh BS,Jeon JE,Kim SY,Oh SH

更新日期：2016-12-03 00:00:00

abstract：BACKGROUND:Potentilla fruticosa, also called "Jinlaomei" and "Gesanghua", is widely used as folk herbs in traditional Tibetan medicine in China to treat inflammations, wounds, certain forms of cancer, diarrhoea, diabetes and other ailments. Previous research found P. fruticosa leaf extract (C-3) combined with Ginkgo bi...

journal_title：BMC complementary and alternative medicine

authors： Liu ZH,Wang DM,Fan SF,Li DW,Luo ZW

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Andrographis paniculata (Burm. f.) Nees (APN), a principal constituent of a famous traditional Chinese medicine Fukeqianjin tablet which is used for the treatment of pelvic inflammatory disease (PID), has been reported to have anti-inflammatory effect in vitro. However, whether it has pharmacological effect ...

journal_title：BMC complementary and alternative medicine

authors： Zou W,Xiao Z,Wen X,Luo J,Chen S,Cheng Z,Xiang D,Hu J,He J

更新日期：2016-11-25 00:00:00

abstract：BACKGROUND:The effect and safety of catgut implantation at acupoints o treat allergic rhinitis (ICD-10 code J30.4) remain controversial. Here, we used a sham catgut implantation group to determine whether catgut implantation at acupoints is an effective and safe treatment for allergic rhinitis. METHODS:A randomized do...

journal_title：BMC complementary and alternative medicine

authors： Li X,Liu Y,Zhang Q,Xiang N,He M,Zhong J,Chen Q,Wang X

更新日期：2016-11-10 00:00:00

abstract：BACKGROUND:Liver disease is the major cause of serious health problem leading to morbidity and mortality worldwide and the problem has increased in search for hepatotherapeutic agents from plants. The present study was designed to compare the probable hepatoprotective activity of olive oil and N. sativa oil on CCl4 ind...

journal_title：BMC complementary and alternative medicine

authors： Al-Seeni MN,El Rabey HA,Zamzami MA,Alnefayee AM

更新日期：2016-11-04 00:00:00

abstract：BACKGROUND:Ficus benghalensis L. (Banyan) is a commonly found tree in Eastern Nepal. Its different plant parts are used for various neurological ailments. This study was performed in mice to see its effects in various neuropharmacological parameters. METHODS:Passive-avoidance (memory), Open-field (anxiety), Pentobarbi...

journal_title：BMC complementary and alternative medicine

authors： Panday DR,Rauniar GP

更新日期：2016-11-03 00:00:00

abstract：BACKGROUND:In this study, we aimed to develop a Stigmata Maydis (corn silk) fraction with dual bio-activities against oxidative stress and protein glycation to protect β-cells from diabetes-induced failure. METHODS:Corn silk fractions were prepared by partition and chemically characterised by thin-layer chromatography...

journal_title：BMC complementary and alternative medicine

authors： Chang CC,Yuan W,Roan HY,Chang JL,Huang HC,Lee YC,Tsay HJ,Liu HK

更新日期：2016-11-03 00:00:00

abstract：BACKGROUND:Plant extracts were evaluated on poultry bacteria known to be threatening public health. This is to develop better bio-therapeutic agents from plant origin. METHODS:Bacteria were isolated from water, feed, crop, gizzard and faeces of layer chicken. Isolates of interest (Escherichia coli, Salmonella enteriti...

journal_title：BMC complementary and alternative medicine

authors： Abiala M,Olayiwola J,Babatunde O,Aiyelaagbe O,Akinyemi S

更新日期：2016-10-26 00:00:00

abstract：BACKGROUND:Breast cancer is the most common type of malignancy in women worldwide. Euphorbia humifusa Willd (EuH) is a plant that is widely used as a traditional medicine. However, no systemic studies on the anti-cancer effects of EuH have been reported. The aim of this study is to evaluate the anti-metastatic effect o...

journal_title：BMC complementary and alternative medicine

authors： Shin SY,Kim CG,Jung YJ,Jung Y,Jung H,Im J,Lim Y,Lee YH

更新日期：2016-10-24 00:00:00

abstract：BACKGROUND:The Rubiaceae family has played a significant role in drug discovery by providing molecules with potential use as templates for the development of therapeutic drugs. This study was designed to study the in vitro synergistic effect of six Rubiaceae species in combination with a known anti-TB drug. The antioxi...

journal_title：BMC complementary and alternative medicine

authors： Aro AO,Dzoyem JP,Eloff JN,McGaw LJ

更新日期：2016-10-03 00:00:00

abstract：BACKGROUND:Herbal materials should be stored at optimal conditions in order to retain their nutritional quality. Proper storage has a significant impact on the quality of the herbs and spices. METHODS:The effects of storage temperature (5 and 15 °C) and time (4 and 8 months) on the phytochemical constituents associate...

journal_title：BMC complementary and alternative medicine

authors： Ghasemzadeh A,Jaafar HZ,Rahmat A

更新日期：2016-09-29 00:00:00

abstract：BACKGROUND:Natural products have being used as potential inhibitors against carbohydrate-hydrolyzing enzymes to treat diabetes mellitus. Chinese dark tea has various interesting bioactivities. In this study, the active compounds from Qingzhuan dark tea were separated and their anti-diabetic activity was examined using ...

journal_title：BMC complementary and alternative medicine

authors： Liu S,Yu Z,Zhu H,Zhang W,Chen Y

更新日期：2016-09-29 00:00:00

abstract：BACKGROUND:Mineral based preparations are widely used for centuries as antimicrobial agents. However, the efficacy and the mode of action of mineral based preparations are uncertain due to the insufficient antimicrobial studies. Arogyawardhana Vati (AV) and Manikya Rasa (MR) are such two Rasashastra herbo-minerallic dr...

journal_title：BMC complementary and alternative medicine

authors： Wijenayake AU,Abayasekara CL,Pitawala HM,Bandara BM

更新日期：2016-09-15 00:00:00

abstract：BACKGROUND:Court-type Thai traditional massage (CTTM) has specific major signal points (MaSP) for treating musculoskeletal conditions. The objectives of this study are to investigate the anatomical surfaces and structures of MaSPs, and to examine blood flow (BF) and skin temperature (ST) changes after applying pressure...

journal_title：BMC complementary and alternative medicine

authors： Plakornkul V,Vannabhum M,Viravud Y,Roongruangchai J,Mutirangura P,Akarasereenont P,Laohapand T

更新日期：2016-09-15 00:00:00

abstract：BACKGROUND:Consumption of plant-derived nutraceuticals and crude drugs in traditional medicine is widely believed to confer beneficial effects in thwarting the progression of cardiovascular diseases. Rhus tripartita (family Anacardiaceae) has been traditionally used to treat a wide range of ailments. METHODS:In the pr...

journal_title：BMC complementary and alternative medicine

authors： Shahat AA,Alsaid MS,Rafatullah S,Al-Sohaibani MO,Parvez MK,Al-Dosari MS,Exarchou V,Pieters L

更新日期：2016-09-08 00:00:00